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August 15, 2025Open Access

Supplementary Fig. S28 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer

Xianfeng Xu Caiwang Yan Lijun Bian Zhe Li Yuhui Yu Xia Zhu Yun Gao Hao Xu Fengyuan Li Yao Liu Ping Sun Zheng Wang Yao Fu Yue Jiang Juncheng Dai Hongxia Ma Zhibin Hu Hongbing Shen Gang Li Cheng Wang Guangfu Jin

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Key Points

Gastric cancer characteristics evolve through specific protein changes associated with intestinal metaplasia.
Key genomic findings include alterations in RNF43, MAP2K7, ARID1A, and ERBB2 impacting disease progression.
Phylogenetic analysis illustrates the evolutionary relationships of key gene alterations central to gastric cancer development.
These insights may lead to new biomarker identification for early detection and treatment strategies in gastric cancer.

Implication

Genomic analysis reveals protein changes and evolutionary traits in intestinal metaplasia and gastric cancer, suggesting novel biomarkers.

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Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd10e https://doi.org/10.1158/0008-5472.29919150

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. S29 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
2Supplementary Fig. S26 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
3Supplementary Fig. S22 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
4Supplementary Fig. S19 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
5Supplementary Fig. S10 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025

Supplementary Fig. S23 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S11 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S18 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025