August 14, 2025BiologyOpen Access

Development, Molecular Docking, and Anti-Anemia Potential of Polyherbal Formulation

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Molecular docking reveals polyherbal formulation enhances erythropoiesis in anemic rats, indicating a safer treatment alternative.

Polyherbal formulation significantly restored RBCs and hemoglobin levels in hemolytic anemia model, showcasing its anti-anemic properties.
With a binding affinity of −6.4 kcal/moL, rutin outperformed traditional iron therapies in molecular docking studies, indicating potential efficacy.
Assessment involved detailed molecular docking techniques with compounds docked against the target protein 6MOE, showing stable bindings.
Findings suggest that the polyherbal formulation could improve iron metabolism and alleviate oxidative stress, providing a promising treatment option.

Bharati et al. (2025) studied this question.

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