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Molecular Characterization of Biofilm-related Virulence and Resistance genes in Candida albicans Isolates from Women with Vulvovaginitis

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Case control analysis indicates high prevalence of virulence and resistance genes in Candida albicans, suggesting new antifungal targets.

A significant prevalence of virulence and resistance genes was found in Candida albicans from women with vulvovaginitis.
The study revealed 70% prevalence of Candida species in the case group and 32% in controls, indicating a notable difference.
Using Hicrome differential agar and Polymerase chain reaction, specific virulence and resistance genes were identified in 125 samples from high vaginal swabs.
The findings highlight the urgent need for new antifungal drugs targeting these virulence and resistance genes identified in Candida albicans.

Ahmadessa et al. (2025) studied this question.

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