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September 10, 2025BMC MicrobiologyOpen Access

Genetic diversity and antifungal resistance in Candida albicans from VVC cases in Indian women

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Authors

BSBiraja Kumar SahuUMUtkalika MallickRHRashmi S. Hegde

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Overview

This study reveals genetic diversity and high antifungal resistance in C. albicans from VVC patients, suggesting monitoring needs.

Key Points

  • C. albicans shows significant genetic variability, with unique characteristics in strain S95.
  • Nystatin exhibited the highest sensitivity at 60%, while ketoconazole and voriconazole had the highest resistance at 60%.
  • Analysis used genetic markers like ISSR and RAPD along with the Kirby-Bauer disk diffusion method to assess resistance patterns.
  • Continuous monitoring of genetic diversity and resistance trends is crucial for effective VVC treatments.

Cite This Study

Sahu et al. (2025) studied this question.

synapsesocial.com/papers/68c1d03554b1d3bfb60f6c84https://doi.org/10.1186/s12866-025-04256-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular Characterization of Biofilm-related Virulence and Resistance genes in Candida albicans Isolates from Women with Vulvovaginitis2025
  2. 2Vulvovaginal Candidiasis: Characterization of Etiologic Agent with Their Antifungal Susceptibility Pattern2025 · 1 citations
  3. 3Vulvovaginal Candidiasis Among Patients Attending the Gynecology Outpatient Department (GOPD) and STD Clinic With Special Reference to Their Antifungal Susceptibility and the Genetic Diversity of Non-albicans Candida in a Tertiary Care Hospital2026
  4. 4Antifungal susceptibility profile of <i>Candida</i> species isolated from women with vulvovaginal candidiasis2024 · 2 citations
  5. 5Resistant C. albicans implicated in recurrent vulvovaginal candidiasis (RVVC) among women in a tertiary healthcare facility in Kumasi, Ghana2024 · 16 citations