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August 22, 2025NutrientsOpen Access

Probiotic and Vitamin D Ameliorate TNBS-Induced Colitis by Targeting Mucosal Barrier and Neutrophil Infiltration

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Combined probiotic and vitamin D reduced colonic damage in a colitis model, suggesting benefits in inflammatory bowel disease management.

Probiotic and vitamin D supplementation decreased colonic damage and neutrophil activity in mice with colitis.
On day 10, mice showed reduced damage after receiving treatment, highlighting the potential therapeutic effects.
Experiment used C57BL/6 mice with TNBS-induced colitis to evaluate the interventions' effectiveness over a week.
Findings emphasize that the combination strategy may provide protection for managing inflammatory bowel disease.

López-Carrasquillo et al. (2025) studied this question.

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