This report demonstrates efficient C-P cross-coupling to form tertiary phosphine oxides using a copper catalyst, highlighting high atomic economy.
The first report of a direct C-P cross-coupling between unprotected phenols and a P(O)H compound to form valuable tertiary phosphine oxides using a copper catalyst without the use of P-ligands is presented. This method is simple to operate and exhibits high atomic economy.
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Xiaoyun He (2025) studied this question.
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