Case report demonstrates complete response to R-CHOP chemotherapy in primary lymphoma of the uterine cervix, indicating effective treatment strategies.
Primary lymphoma of the uterine cervix (LUCX) is a rare disease and can be challenging to diagnose. Cytology is not a sensitive screening tool and instead deep or excisional biopsy is recommended for diagnosis. Treatment typically includes chemotherapy with combination cyclophosphamide, doxorubicin, vincristine, prednisone, and rituximab (R-CHOP) and can be followed by radiation or surgery if deemed necessary. We present the case of a patient diagnosed with LUCX who underwent R-CHOP chemotherapy followed by surgery with complete response noted on final pathology.
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Christine et al. (2025) studied this question.
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