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July 25, 2025Research Journal of Pharmaceutical Dosage Forms and Technology

Formulation and Characterization of Polymeric Microspheres Loaded with Sesamol for Improving Bioavailability

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Authors

GKGagan KukloriaKSKavita SavkareSKSonam Kukloria

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Overview

Formulation of microspheres using chitosan and sodium alginate improved drug release, suggesting better bioavailability.

Key Points

  • In vitro drug release from the microspheres ranged from 94.36% to 98% over 12 hours, indicating significant bioavailability enhancement.
  • Average particle sizes of the formulations were between 29.88 µm and 35.36 µm, allowing for effective delivery.
  • The ionic gelation process was employed to create microspheres that efficiently encapsulated sesamol for drug delivery.
  • Chitosan and sodium alginate as a polymeric matrix potentially support prolonged release of sesamol, enhancing therapeutic effectiveness.

Cite This Study

Kukloria et al. (2025) studied this question.

synapsesocial.com/papers/68af59ddad7bf08b1eadeac0https://doi.org/10.52711/0975-4377.2025.00025
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