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Role of CRP and WBC in the Diagnosis of Acute Appendicitis: A Retrospective Study at a Military Hospital in North East India

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Retrospective study assesses diagnostic value of CRP and WBC in 100 suspected appendicitis cases, suggesting limitations.

CRP and WBC are inadequate for diagnosing appendicitis, highlighting the need for clinical judgment.
Sensitivity for CRP at ≥10 mg/L is 70%, while WBC at ≥11×10⁹/L shows 60% sensitivity.
ROC analysis reveals poor accuracy with AUC around 0.5, indicating unreliable diagnostic performance.
Logistic regression finds no significant predictive value for either CRP or WBC in appendicitis cases.

Walia et al. (2025) studied this question.

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