Key result
Elevated C reactive protein (>25 mg/dl) was found in 92.8% of complicated acute appendicitis cases compared to 37.8% of uncomplicated cases, serving as a marker for disease severity.
Why the study?
Do pre-operative CRP and WBC count predict the severity of acute appendicitis?
Population
51 patients admitted with clinical diagnosis of acute appendicitis. Excluded: patients presenting with…
Design
Cross-sectional
Authors
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May support CRP/WBC use in suspected appendicitis diagnosis; leaves open optimal thresholds for severity prediction in prospective studies.
Observational (n=51)
Do pre-operative CRP and WBC count predict the severity of acute appendicitis?
Pre-operative CRP and WBC count are useful markers for diagnosing acute appendicitis and predicting its severity, with higher values strongly associated with complicated disease.
Vikramathithan et al. (2017) conducted an observational in Acute appendicitis (n=51). C reactive protein and WBC count was evaluated on Diagnosis and severity of acute appendicitis based on histopathology (complicated vs uncomplicated). Elevated C reactive protein (>25 mg/dl) was found in 92.8% of complicated acute appendicitis cases compared to 37.8% of uncomplicated cases, serving as a marker for disease severity.
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