Single case study implements MOHO to improve rehabilitation outcomes in acute medical unit for MELAS syndrome patients, suggesting better individualized care strategies.
Background Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS) syndrome presents unique challenges in acute medical units due to its complex medical, neurological, and cognitive impairments. The fast-paced, often chaotic environment of AMUs can hinder continuity of care and limit access to specialized rehabilitation resources. Methods This case study describes the medical course and explores the application of the Model of Human Occupation (MOHO) in enhancing rehabilitation outcomes for a 45-year-old male with MELAS syndrome in an acute medical unit in the United Kingdom. Results Following a cardiac arrest and subsequent intensive care unit stay, occupational therapy interventions, guided by MOHO, were implemented to address the patient’s complex needs. Strategies included errorless learning, specific skill training, family-inclusive therapy, and environmental aids, habit and routine training, activities of daily living, functional mobility, and life roles. Discussion This case describes the use of MOHO in an acute care setting and application in occupational therapy assessment and intervention. Results underscore the potential of MOHO in acute care, advocating for its continued use to optimize outcomes, facilitate individualized care, and enhance discharge planning for patients with complex needs like MELAS syndrome.
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Lin et al. (2025) studied this question.
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