The Structure and Dynamics of Sexually Transmitted Diseases, Using the Example of Trichomoniasis, Isolated in Persons of the Clinical Perinatal Center Pskov Region

Introduction. The incidence of sexually transmitted infections (STIs) continues to rise and poses a serious public health concern, particularly in developing countries, leading to infertility and ectopic pregnancies. Preventing the spread of STIs, along with early detection and appropriate treatment, can minimize the damage to the reproductive tract caused by these infections and simultaneously improve the health of women and men worldwide. Objectives. The aim was to assess the quality of laboratory diagnostics of sexually transmitted diseases using the example of trichomoniasis. Methods. The study is based on bacteriological, bacterioscopic, and molecular genetic research methods. The work analyzes the results of 115443 urogenital swabs and PCR tests for trichomoniasis, and also studies the main biochemical indicators of this infection in a dynamic observation. Results and discussions. The statistical data obtained during the experimental work allowed us to conclude that the number of patients with trichomoniasis decreased between 2021 and 2023. The study of biochemical indicators revealed a decrease in the average number of white blood cells in the blood before and after treatment in pregnant women with Trichomonas vaginalis. For example, before treatment, the indicator was 11.0 x 109/l, and after treatment, it was 7.8 x 109/l. The erythrocyte sedimentation rate before treatment was between 12 and 15 mm/h, and after treatment, it was between 8 and 10 mm/h. The average number of leukocytes in the urogenital smear before treatment was 47 cells per field of vision, and after treatment, it was 12 cells. The average number of epithelial cells in the urogenital smear was 30 cells per field of vision before treatment, and 1 cell after treatment. A similar trend was observed in the group of non-pregnant women. The average leukocyte count before treatment was 11.0 x 109/L, and 7.0 x 109/L after treatment, and the erythrocyte sedimentation rate decreased by almost.