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August 25, 2025Frontiers in ImmunologyOpen Access

Rapid early remission in a patient with severe aplastic anemia: a case report of hetrombopag, cyclosporine, and danazol combination therapy

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Authors

YDYuting DaiQGQiang GuoXGXiaoxiao Guo

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Overview

Case report reveals improved outcomes in severe aplastic anemia patients treated with hetrombopag and immunosuppressive therapy.

Key Points

  • Complete remission was achieved at 6 months for a 28-year-old male with severe aplastic anemia, indicating significant effectiveness of the therapy.
  • The patient showed a partial response at 3 months, with hematologic assessments confirming the positive outcome of the combination treatment.
  • Combination therapy included CSA, hetrombopag, and danazol, with no severe adverse events reported during treatment.
  • This promising case points to the need for larger clinical trials to evaluate the efficacy of this ATG-free regimen for SAA.

Cite This Study

Dai et al. (2025) studied this question.

synapsesocial.com/papers/68af5f07ad7bf08b1eae177dhttps://doi.org/10.3389/fimmu.2025.1609771
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