SABRE method achieved 0.47% 15N polarization in SDAP, suggesting effective in-magnet hyperpolarization techniques.
Nuclear magnetic resonance (NMR) suffers from its low sensitivity which can be dramatically increased by the nuclear spin hyperpolarization. Signal amplification by reversible exchange (SABRE) is a hyperpolarization technique based on the rational usage of parahydrogen as a source of hyperpolarization. This work reports in-magnet 15N polarization (0.47%) of 3-methyl-[1,2,4]-selenadiazolo-[4,5-a]-pyridin-4-ium bromide (SDAP) and its 77Se satellites obtained by the SABRE with RF excitation of 1H and 15N nuclear spins.
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Markelov et al. (2025) studied this question.
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