January 1, 2025

Antidiabetic Potential of Azadirachta indica Aqueous Stem-Bark Extract Streptozotocin-Induced Diabetic Wistar Rats

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Authors

UZUmar Sani ZangoFederal Medical Centre ZAZ.A. AbubakarFederal University Dutse SYSalahuddeen Ya’uUmaru Musa Yar'adua University

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Implication

This study evaluates the antidiabetic effects of Azadirachta indica extract on blood glucose in STZ-induced diabetic Wistar rats, suggesting significant health implications.

Key Points

Administration of Azadirachta indica extract significantly lowers blood glucose levels in diabetic Wistar rats, reversing the effects of streptozotocin.
Treatment with 100, 300, and 400 mg/kg A. indica extracts showed a notable decrease in fasting blood glucose compared to control groups.
The approach involved administering A. indica extract and glibenclamide to Wistar rats over a 4-week period, monitoring blood glucose levels weekly.
These findings highlight the potential of A. indica extract for managing diabetes and its complications in a controlled model.

Cite This Study

Zango et al. (2025) studied this question.

synapsesocial.com/papers/68af63ddad7bf08b1eae4008 https://doi.org/10.54660/ijabrn.2025.2.4.33-39

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Implication

This study evaluates the antidiabetic effects of Azadirachta indica extract on blood glucose in STZ-induced diabetic Wistar rats, suggesting significant health implications.

Antidiabetic Potential of Azadirachta indica Aqueous Stem-Bark Extract Streptozotocin-Induced Diabetic Wistar Rats

Discussion

Member takes

Implication

Key Points

Cite This Study

Antidiabetic Potential of Azadirachta indica Aqueous Stem-Bark Extract Streptozotocin-Induced Diabetic Wistar Rats

Discussion

Member takes

Implication

Key Points

Cite This Study

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