What type of study is this?

This is a Test-Negative Case-Control Study study.

September 5, 2025JAMA

RSV Vaccine Effectiveness Against Hospitalization Among US Adults Aged 60 Years or Older During 2 Seasons

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Authors

DSDiya SurieCenters for Disease Control and Prevention WSWesley H. SelfVanderbilt University Medical Center KYKatharine A. YuenglingCenters for Disease Control and Prevention

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Implication

This test-negative case-control study found RSV vaccine effectively reduces hospitalization in older adults, suggesting high importance for vaccination.

Key Points

The RSV vaccine reduced hospitalization by 58% during two seasons for adults aged 60 and older, indicating effectiveness.
Among immunocompetent adults, vaccine effectiveness was 67%, but only 30% for the immunocompromised, highlighting disparity.
Analysis involved 6958 adults hospitalized for acute respiratory illness across 26 hospitals in 20 US states, focusing on RSV cases.
Lower vaccine effectiveness was observed in those with cardiovascular disease, indicating a need for tailored vaccine strategies.

Cite This Study

Surie et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a2b2b87ece8dc95484e https://doi.org/10.1001/jama.2025.15896

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Implication

This test-negative case-control study found RSV vaccine effectively reduces hospitalization in older adults, suggesting high importance for vaccination.

RSV Vaccine Effectiveness Against Hospitalization Among US Adults Aged 60 Years or Older During 2 Seasons

Discussion

Member takes

Implication

Key Points

Cite This Study

RSV Vaccine Effectiveness Against Hospitalization Among US Adults Aged 60 Years or Older During 2 Seasons

Discussion

Member takes

Implication

Key Points

Cite This Study

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