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The article presents the results of a comparative analysis of the clinical and diagnostic features of cardiovascular pathology in patients of different sexes. The study encompasses the assessment of key clinical indicators, laboratory data, and instrumental examinations (echocardiography, Holter ECG monitoring, and coronary angiography), as well as quality-of-life indicators in patients with ischemic heart disease. It was found that women less frequently had a history of recurrent myocardial infarction and demonstrated significantly higher quality-of-life scores according to the EQ-VAS. At the same time, women showed a less favorable lipid profile, particularly higher total cholesterol levels, which requires enhanced prevention and control. Echocardiographic data indicated a better structural and functional state of the heart in women (higher left ventricular ejection fraction and smaller chamber sizes), while Holter monitoring showed shorter ischemic episodes and better autonomic regulation. Digital ECG analysis and coronary angiography data revealed certain sex-related differences in myocardial and coronary artery involvement. These findings emphasize the need to consider sex-specific characteristics in the diagnosis, treatment, and secondary prevention of ischemic heart disease.
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Тащук et al. (2025) studied this question.
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