Case reveals C. perfringens infection following an orthopedic injury, suggesting increased vigilance in closed fractures.
Case We present a case of a closed, farm-related orthopedic injury that was complicated by C. perfringens infection. With staged surgical procedures and intravenous antibiotics, the infection was successfully eradicated, and the fracture went onto successful union. Conclusion Clostridium perfringens is a Gram-positive, anaerobic, spore-forming bacteria that is ubiquitous in the environment. C. Perfringens infections usually manifest as necrotizing fasciitis in orthopedic settings, but it may also lead to post-traumatic soft tissue and bony infections after closed fractures. This case demonstrates that delayed anaerobic infections should not be overlooked in the agricultural patient population even in closed fractures.
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Chung et al. (2025) studied this question.
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