TTP4.09 Comparison of the Accuracy of Boey Score, Modified Boey Score (Mboey) and Pulp Score in Predicting In-Hospital Mortality in Patients with Perforated Peptic Ulcer Disease Who Underwent Surgery in a Tertiary Hospital: A Retrospective Cohort Study

Introduction Perforation is the second most common complication of peptic ulcer disease. It presents with bacterial peritonitis with a high mortality rate. This study aims to help clinicians predict in-hospital mortality of patients with perforated peptic ulcer disease (PPUD) preoperatively by using BOEY, mBOEY and PULP scoring systems. Methodology This is a retrospective cohort study wherein data of adult PPUD patients who underwent surgery were analyzed using BOEY, mBOEY and PULP scoring systems. Results A total of 96 patients were included in the study. Fourteen patients died with an incidence rate of 14.58%. Multivariable analysis showed that the highest AUC value was observed for PULP (AUC=0.96; 95%) followed by mBOEY (AUC=0.91; 95%), and BOEY (AUC=0.90; 95%). PULP score showed the highest accuracy and specificity in relation to mortality prediction. However, its sensitivity (71.43%) was lower than that of BOEY (85.71%) and mBOEY (100%). Conclusion Perforated peptic ulcer disease is a life-threatening condition which may cause significant mortality. The BOEY, mBOEY and PULP scoring are all efficient criteria in prognosticating patients with PPUD. The BOEY and mBOEY scores are user-friendly and utilize data that are readily available. Though PULP score is more complicated to use, it is more specific in predicting mortality in patients with PPUD. We can conclude that these three scoring criteria can be used in prognosticating patients with PPUD, but PULP score is the most effective.