TTP2.15 Index CRP and clinical severity scoring in acute diverticulitis patients in a tertiary care hospital

Aim C-reactive protein (CRP) has been found to be a useful marker in the prediction of the inflammation grade and severity of acute diverticulitis. The study aims to identify the index CRP levels of patients presenting with acute diverticulitis and prediction of the clinical severity and management options. Methods Retrospective observational study. Was registered as a QI project with the JCUH. Inclusion criteria were Inclusion criteria – Patients admitted to the general surgery department, with CT confirmed diverticulitis, at JCUH from March 2023 to October 2024. A total of 189 patients’ data was evaluated. Exclusion criteria – Patients with past medical history of diverticulosis, patients with CT confirmed diverticulosis. All other emergency and elective admission to general surgery department at JCUH were also excluded. Variables collected include age, sex, ASA grade, length of stay, Index CRP, highest CRP, index WCC, highest WCC, neutrophil count, index albumin, Hinchey score, conservative management, IR drainage, surgical management. Statistics was performed on StatsDirect3 software. Results Multivariate-regression-analysis between surgical vs IR drainage had a p-value <0.05 with Hinchey scoring, index WCC and index albumin value. Index WCC, index CRP, neutrophil count and albumin value had a p-value <0.001 for the Hinchey scoring. Index-CRP, index-WCC, neutrophil count and albumin values are statistically significant factors in predicting the Hinchey score of the patients. In our study, patients with Index CRP >178, WCC >16.1, neutrophil count >12 and albumin <31 needed either IR drainage or surgery. Index CRP >194, WCC >19.1, neutrophil count >17.4 and albumin <23 required surgery.