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September 5, 2025Turkish Journal of HematologyOpen Access

Clinical and Prognostic Features of Erythrodermic Cutaneous T-Cell Lymphoma: A Retrospective Study of 35 Patients

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Authors

HŞHatice ŞanlıBahçeşehir UniversityHMHandan Merve Erol MartAnkara UniversityDCDerya CaglarBoston Children's Hospital

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Implication

Retrospective analysis evaluates survival outcomes and prognostic indicators in erythrodermic cutaneous T-cell lymphoma, indicating challenges in differentiation between subgroups.

Key Points

  • Most patients presented with advanced-stage erythrodermic cutaneous T-cell lymphoma, with a poor overall prognosis and no significant survival differences among subgroups.
  • Key prognostic indicators include elevated serum LDH and beta-2 microglobulin levels, as well as female sex and eosinophilia as independent mortality predictors.
  • Statistical analyses used included Kaplan-Meier survival estimates and Cox regression models to assess clinical features and progression patterns in patients.
  • Findings highlight the challenges of diagnostic accuracy and treatment strategies for erythrodermic cutaneous T-cell lymphoma, emphasizing the need for larger studies.

Cite This Study

Şanlı et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a432b87ece8dc955527https://doi.org/10.4274/tjh.galenos.2025.2025.0193
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1[What's new about cutaneous T-cell lymphoma?]2025
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  3. 3Immune pathways, current and potential therapies in Mycosis fungoides and Sezary syndrome2025 · 2 citations
  4. 4Genomic landscape of mycosis fungoides2025
  5. 5Pathology of Cutaneous T Cell Lymphoma: A Narrative Review2026 · 2 citations