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September 5, 2025MicroorganismsOpen Access

Clostridium butyricum Supplementation Reduces Diarrhea in Preweaning Calves by Modulating Fecal Short-Chain Fatty Acids and Gut Microbiota

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Authors

PGPeiyun GaoShihezi UniversitySPShengjiang PangResearch Institute of Tropical ForestryQWQianqian WangAnhui Agricultural University

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Implication

Observational analysis revealed that C. butyricum reduces diarrhea incidence in preweaning calves, suggesting benefits for gut microbiota.

Key Points

  • Calves receiving 5 g/d of C. butyricum had a 7.74% lower diarrhea incidence than controls during the study.
  • Average daily gain was significantly higher in the 5 g/d group compared to control (804.67 vs. 701.67 g/d).
  • Serum immunoglobulin levels were increased in the C. butyricum group, alongside enhanced antioxidant capacity.
  • Fecal levels of beneficial short-chain fatty acids and specific gut bacteria were elevated with C. butyricum supplementation.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a492b87ece8dc955709https://doi.org/10.3390/microorganisms13091993
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