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Diabetes Mellitus and Infectious Diseases: Current Evidence and Clinical Implications

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Individuals with diabetes face a 1.5- to 4-fold increased risk of both common and severe infections, leading to worse outcomes.
Chronic hyperglycemia impairs neutrophil function and tissue integrity, increasing susceptibility to infections.
Management of infections in diabetics should be individualized, balancing glycemic control with infection risk.
Preventive care for individuals with diabetes emphasizes comprehensive vaccination and regular foot surveillance to mitigate complications.

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Observational analysis shows increased infection risk in individuals with diabetes, highlighting unique clinical implications.

Kim et al. (2025) studied this question.

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