Case report highlights cutaneous necrosis and acrocyanosis in a child with cold agglutinin syndrome, suggesting urgent care is necessary.
Acrocyanosis and gangrene are rare but serious manifestations of CAS caused by MP infection in children. These symptoms may lead to severe complications if not managed appropriately, highlighting the need for clinicians to remain vigilant and provide proper supportive care. In the case we discussed, the administration of FFP, plasmapheresis, corticosteroids, and IVIG led to a satisfactory improvement in the patient's condition.
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Abtahi‐Naeini et al. (2025) studied this question.
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