Case report reveals cold agglutinin urticaria following Mycoplasma pneumoniae infection in a child, highlighting the importance of identifying post-infectious autoimmune complications.
This case report discusses a 13-year-old child presenting with bilateral middle-basal pneumonia attributed to Mycoplasma pneumoniae infection. Despite the absence of hemolysis, the patient exhibited symptoms consistent with cold agglutinin syndrome (CAS), including an erythematous-pomfoid urticaria-like rash. Laboratory analyses confirmed CAS with elevated cold agglutinin titers and a recent Mycoplasma pneumoniae infection. Treatment with clarithromycin resolved the pneumonia, and the rash spontaneously regressed. Additionally, hepatic steatosis was detected, likely associated with the patient's overweight status. This case highlights the importance of considering CAS in children with atypical symptoms following Mycoplasma pneumoniae infection.
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Cusmano et al. (2024) studied this question.
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