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September 5, 2025Advanced Chinese MedicineOpen Access

Network pharmacology‐based screening and pharmacokinetic evaluation of key active compounds in Jinhong tablets against chronic superficial gastritis

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Authors

TZTingyu ZhangJFJian Q. FengMQMengyu Qian

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Overview

This study evaluates pharmacokinetic characteristics of Jinhong tablets in normal and CSG rats, suggesting impacts on active compounds.

Key Points

  • Jinhong tablets demonstrated linear pharmacokinetic properties within specified dose ranges while affecting chronic superficial gastritis.
  • Seven active compounds were identified, with notable pharmacokinetic differences observed between normal and CSG rats.
  • The study established a network pharmacology framework to analyze key ingredients in treating chronic superficial gastritis.
  • Gut microbiota changes were linked to the pharmacokinetic profiles of Jinhong tablet compounds in different rat conditions.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68bb3d4e2b87ece8dc955d39https://doi.org/10.1002/acm4.35
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