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September 5, 2025Open Access

Sex and regional effects of Bacteroides in the gut

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Authors

RVRebecca VallsKBKaitlyn E. BarrackGOGeorge A. O’Toole

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Overview

Study shows that Bacteroides influences gut microbiota composition in mice, highlighting sex-related immune responses.

Key Points

  • Bacteroides colonization significantly alters gut microbiota and immune responses in mice.
  • C57BL/6 mice treated with antibiotics showed increased Bacteroides in the colon, impacting inflammation.
  • Differential gene expression analysis revealed sex-dependent immune responses localized in the cecum.
  • Findings suggest Bacteroides could lead to innovative therapies targeting gut and systemic health.

Cite This Study

Valls et al. (2025) studied this question.

synapsesocial.com/papers/68bb3d4e2b87ece8dc955d6fhttps://doi.org/10.1101/2025.08.27.672693
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