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September 5, 2025Italian Journal of MedicineOpen Access

P25 | An expected case of severe rhabdomyolysis

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Case report describes rhabdomyolysis in a 77-year-old man treated with statins, indicating potential risks of high-intensity statin use.

Severe rhabdomyolysis occurred after starting rosuvastatin/ezetimibe therapy in a 77-year-old man.
Pre-treatment levels showed drastic increases in creatinine (9.37 mg/dL) and CPK (99520 U/L), highlighting severe muscle damage.
The patient required hemodialysis for acute renal failure, linking it directly to statin use and emphasizing careful prescribing.
Resolution of symptoms was achieved post-therapy adjustment, indicating potential for recovery from statin-induced complications.

A 2025 study studied this question.

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