Case report discusses primary mantle cell lymphoma presentation in a patient with bilateral tonsillar enlargement and subcutaneous swelling, indicating rare extranodal disease occurrence.
Mantle cell lymphoma (MCL), a subtype of non-Hodgkin’s lymphoma (NHL), accounts for almost 5%–7% of all the NHL diagnosed cases, with 70% of cases seen in men aged between 60 and 70 years. Nearly 25% of the cases show extranodal disease as the primary presentation. Extranodal involvement of Waldeyer’s ring, salivary glands, lacrimal gland, orbit, skin, thyroid, breast, pleura, and spleen is very rare. Cutaneous or subcutaneous lesions or lesions in the oral cavity as presenting features are exceedingly rare, and thorough clinical examination should be done for any other synchronous swellings. Immediate satisfactory evaluation is utmost to provide the patient with the best possible outcome. This case report helps us further broaden our understanding of the spectrum of clinical presentation of MCL. We report a case of primary MCL that presented with bilateral tonsillar enlargement with a subcutaneous left upper back swelling.
No takes yet. Share an insight, caveat, or question.
Mandal et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: