Mantle cell lymphomas are mature B-cell neoplasms that exhibit an aggressive clinical behavior and overexpression of cyclin D1 protein. Although lymphadenopathy is the most typical manifestation of the disease, Primary extranodal disease is seen in approximately 25% of cases, while presentation at sites other than these primary extranodal sites is uncommon and typically involves the salivary glands, skin, thyroid, orbit, breast, epidural space, pleura, and spleen. Involvement of neck muscle tissue is extremely rare, and to our knowledge, we present the first reported case of CML presenting as a mass in the posterior cervical muscles.
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Filali et al. (2024) studied this question.
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