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September 5, 2025Cardiovascular Endocrinology & MetabolismOpen Access

Genetic, neuropeptidergic, and cardiometabolic interplay in female central precocious puberty

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Authors

AMAygun Khaleddin MusayevaMAMahira Amirova

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Overview

Analysis reveals genetic mutations and neuropeptide roles in central precocious puberty, suggesting interventions for cardiometabolic outcomes.

Key Points

  • Central precocious puberty is linked to significant cardiometabolic health concerns in females.
  • Genetic mutations, particularly in genes like MKRN3 and KISS1, are major factors in CPP.
  • Neuropeptides, especially kisspeptin, are crucial for regulating the onset of puberty.
  • Early intervention and diagnosis can significantly mitigate cardiovascular risks associated with CPP.

Cite This Study

Musayeva et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef02b87ece8dc95772dhttps://doi.org/10.1097/xce.0000000000000343
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of first-year GnRHa therapy in girls with idiopathic central precocious puberty diagnosed after age 8: a retrospective study2025 · 3 citations
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  3. 3Approach to the Patient: Central Precocious Puberty2023 · 30 citations
  4. 4Childhood obesity and central precocious puberty2022 · 132 citations
  5. 5Kisspeptin‐54 Levels are increased in Patients with Colorectal Cancer2012 · 23 citations