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September 5, 2025Cancer Immunology ResearchOpen Access

Targeting Myeloid Cells for Cancer Immunotherapy

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Authors

LBLucas BlanchardAMAndrew MijacikaJOJuan C. Osorio

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Overview

This review discusses how targeting myeloid cells can improve antitumor responses in cancer immunotherapy, highlighting emerging antibody-based therapies.

Key Points

  • Targeting myeloid cells can enhance antitumor responses in cancer immunotherapy.
  • Recent advances in immune profiling show myeloid cells exhibit remarkable diversity and plasticity.
  • Emerging antibody-based therapies for myeloid cells advance cancer treatment into clinical development.
  • Optimizing myeloid cell engagement through Fc-engineering may amplify immune effector functions.

Cite This Study

Blanchard et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef72b87ece8dc95787fhttps://doi.org/10.1158/2326-6066.cir-25-0159
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Targeting myeloid cells to improve cancer immune therapy2025 · 23 citations
  2. 2Potential therapeutic targets in myeloid cell therapy for overcoming chemoresistance and immune suppression in gastrointestinal tumors2024 · 5 citations
  3. 3Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity2024
  4. 4Inflammation and Myeloid Cells in Cancer Progression and Metastasis2022 · 37 citations
  5. 5Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity2024