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September 5, 2025Open Access

A single centre randomised, feasibility study using point-of-care (POC) testing for respiratory viruses to direct oral corticosteroids use in preschool-aged children with acute wheeze. A Protocol.

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Randomized trial tests oral corticosteroid use linked to respiratory viruses in preschoolers, indicating future study potential.

Participants receiving the appropriate treatment based on respiratory virus testing may improve management of wheezing.
The trial will assess recruitment and adherence outcomes, with data gathered from clinical reviews and follow-ups.
Conducting rapid respiratory virus tests before treatment decisions could better guide the use of corticosteroids in children.
This feasibility study aims to inform a larger multi-centre trial on the role of respiratory virus testing in preschool wheeze management.

Norman-Bruce et al. (2025) studied this question.

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