Why the study?
Does oral prednisolone reduce time until ready for discharge in hospitalized children with virus-positive recurrent wheezing?
Population
59 hospitalized children with recurrent wheezing and virus-positive, mean age 2.6 years.
Comparison
Oral prednisolone vs Placebo
Design
RCT, randomized
Follow-up
2 months
Authors
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Does not support routine prednisolone in virus-positive wheezing; subgroup benefits leave confirmation to prospective virus-stratified trials.
Does oral prednisolone reduce time until ready for discharge in hospitalized children with virus-positive recurrent wheezing?
Prednisolone may reduce the time to discharge in children hospitalized for recurrent wheezing specifically associated with picornavirus or enterovirus infections, though prospective trials are needed.
Jartti et al. (2007) studied this question.
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