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September 5, 2025Italian Journal of MedicineOpen Access

P06 | Development of wet beriberi with prolonged Qtc and severe LVEF in a Wernicke’s encephalopathy patient

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Overview

Case report highlights heart failure with severe LVEF and QTc prolongation in wet beriberi, suggesting monitoring is crucial.

Key Points

  • Severe thiamine deficiency led to wet beriberi and a severe reduction in LVEF to 25%.
  • The patient exhibited a prolonged QTc of 650 msec along with lactic acidosis (lac 6 mMol/L).
  • Empiric high-dose IV thiamine treatment resulted in significant improvement in symptoms and LV function within 24 hours.
  • QTc prolongation should be monitored in cases of Wernicke’s encephalopathy with heart dysfunction.

Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/68bb3efd2b87ece8dc957ba1https://doi.org/10.4081/itjm.2025.2196
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