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September 5, 2025Head & NeckOpen Access

Neck Dissection Reduces Risk of Recurrence in Early‐Stage Oral Tongue Cancer

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Authors

JLJaclyn LeeTDTan DingMWMae Wimbiscus

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Overview

Retrospective cohort study shows neck dissection reduces recurrence in oral tongue cancer patients, suggesting a surgical intervention is beneficial.

Key Points

  • Upfront neck dissection leads to a significant reduction in recurrence for early-stage oral tongue cancer patients.
  • At a median follow-up of 56 months, 31% of patients experienced recurrence, with factors like positive margins impacting outcomes.
  • Patients undergoing glossectomy with elective neck dissection had a lower hazard ratio of recurrence, measuring at HR 0.31.
  • Surgical intervention starting at a depth of invasion of 2 mm shows promise, underscoring the need for careful treatment planning.

Cite This Study

Lee et al. (2025) studied this question.

synapsesocial.com/papers/68bb421a2b87ece8dc9585e9https://doi.org/10.1002/hed.70017
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sentinel Lymph Node Biopsy Versus Elective Neck Dissection in Carcinoma of the Tongue and Floor of the Mouth2025 · 2 citations
  2. 2Elective neck dissection in clinically early stage (cT1-T2N0) supraglottic squamous cell carcinomas: a systematic review.2026
  3. 3Bilateral Neck Dissection Effectively Improves Prognosis of Patients With <scp>T3N0M0</scp> Glottic Carcinoma2026
  4. 4Elective Neck Dissection Strategies Guided by AJCC-8 Depth-of-Invasion (DOI) in cT1–T2N0 Oral Cavity Cancer—A Systematic Review2026 · 2 citations
  5. 5Oncologic Outcomes of Salvage Surgery in Recurrent Oral Tongue Squamous Cell Carcinoma2024