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June 20, 2026Surgical OncologyOpen Access

Elective neck dissection in clinically early stage (cT1-T2N0) supraglottic squamous cell carcinomas: a systematic review.

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Authors

JRJuan P. RodrigoFLFernando LópezLKLuiz P. Kowalski

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Overview

Systematic review analyzes elective neck dissection outcomes in early-stage supraglottic carcinoma patients, suggesting a tailored approach.

Key Points

  • This review aims to evaluate the effectiveness of elective neck dissection in early-stage supraglottic squamous cell carcinoma patients who are clinically node-negative.
  • Systematic review of studies published from 2000 to 2025 regarding elective neck dissection versus observation in cT1-T2N0 tumors.
  • Following PRISMA methodology for study selection and analysis.
  • Sixteen studies met the inclusion criteria for evaluation.
  • Occult nodal metastasis was found in 13–37.5% of the patients, primarily at level II.
  • Super-selective dissection of levels II–III improved regional control compared to observation, though overall survival benefits varied.
  • High-risk factors for occult metastasis included T2 classification and poor tumor differentiation.

Cite This Study

Rodrigo et al. (2026) studied this question.

synapsesocial.com/papers/6a362e62db0793dc1a53611fhttps://doi.org/10.1016/j.suronc.2026.102484
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Risk‐Adapted Approach for Elective Neck Dissection in Salvage Total Laryngectomy: Revisiting the Role of Tumor Subsite and Occult Nodal Disease2025
  2. 2Addressing the Neck: An NCDB Study of Clinically Node‐Negative Supraglottic Squamous Cell Carcinoma2024 · 1 citations
  3. 3Elective Neck Dissection in Advanced Cutaneous Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis2025
  4. 4Elective Neck Dissection in Advanced Cutaneous Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis2025
  5. 5Elective Neck Dissection in Patients Undergoing Salvage Laryngectomy: Outcomes, Complications, and Considerations2024