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November 30, 2025Clinical OtolaryngologyOpen Access

Elective Neck Dissection in Advanced Cutaneous Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis

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Authors

SKSeraphina KeyMKMatthew KwokTMTimothy McLean

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Overview

Systematic review reveals no definitive survival benefit of elective neck dissection in cN0 patients with cutaneous squamous cell carcinoma, suggesting further investigation is needed.

Key Points

  • Elective neck dissection did not conclusive improve overall survival in patients with advanced cSCC.
  • In a systematic review of 983 studies, only six met inclusion criteria for meta-analysis and showed a risk of bias.
  • The occult cervical nodal rate was analyzed, showing a rate of 17.34% with moderate confidence intervals.
  • Findings indicate the need for further research to clarify the impact of END on survival outcomes in this patient group.

Cite This Study

Key et al. (2025) studied this question.

synapsesocial.com/papers/692b9da01d383f2b2a37a3c8https://doi.org/10.1111/coa.70063
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