What type of study is this?

This is a In Vitro Study study.

Novel prospectives of Paeonia lactiflora root extract as a natural modulator of LPS-induced inflammation and collagen I synthesis in skin and oral gingival cells

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In vitro study shows P. lactiflora extract reduces inflammation in gingival and skin cells, highlighting its potential as a natural modulator.

Extract of P. lactiflora significantly reduced TRPV1 levels in skin keratinocytes, potentially decreasing inflammation.
Concentrations of 0.5 mg/mL of the extract reduced TNF-α production by 25% and IL-6 by 55%, indicating strong anti-inflammatory properties.
The extract demonstrated a protective effect against collagen destruction, reducing MMP-9 and MMP-8 production by over 70% and 39%, respectively.
Further research could lead to in vivo studies and the development of new formulations to enhance skin health.

Filatov et al. (2025) studied this question.

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In vitro study shows P. lactiflora extract reduces inflammation in gingival and skin cells, highlighting its potential as a natural modulator.