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September 5, 2025Frontiers in ImmunologyOpen Access

Skin immune microenvironment in psoriasis: from bench to bedside

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Authors

YYYi YaoSichuan UniversityLCLi‐Qing ChenUniversity of Illinois Urbana-ChampaignYLYingnan Lv

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Overview

Review explores immune microenvironment and cytokine cascades in psoriasis, highlighting implications for novel therapies.

Key Points

  • Psoriasis pathogenesis involves multiple factors disrupting immune homeostasis, leading to chronic inflammation.
  • Current treatments include conventional methods and targeted biologic agents like TNF-α inhibitors and JAK inhibitors.
  • Identifying biomarkers and managing comorbidities are crucial for improving clinical outcomes in psoriasis patients.
  • Future directions emphasize integrating multi-omics data to develop personalized therapies for better efficacy.

Cite This Study

Yao et al. (2025) studied this question.

synapsesocial.com/papers/68bb42212b87ece8dc958b2ehttps://doi.org/10.3389/fimmu.2025.1643418
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