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September 5, 2025Kuban Scientific Medical BulletinOpen Access

Personalized selection of topical antibacterial agents in patients with microbial eczema based on whole genome sequencing data: A prospective сomparative randomized study

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Authors

ВЛВ.В. ЛазаревМТМ. М. ТлишМШМ. Е. Шавилова

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Overview

Prospective comparative randomized study shows improved Eczema Area and Severity Index in patients using personalized topical therapies, indicating enhanced therapeutic efficacy.

Key Points

  • Personalized selection of topical antibacterial agents leads to faster restoration of healthy skin microbiome in patients with microbial eczema.
  • The main group showed a significant decrease in microbial colonization after 6 months, with greater improvements in beneficial bacteria compared to the control group.
  • Whole genome sequencing provided crucial data on antibiotic resistance, guiding tailored therapy for more effective treatment.
  • The study included 60 patients, with significant differences in therapy outcomes between the main and control groups contributing to innovative treatment approaches.

Cite This Study

Лазарев et al. (2025) studied this question.

synapsesocial.com/papers/68bb42272b87ece8dc958d5ehttps://doi.org/10.25207/1608-6228-2025-32-4-18-32
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