Case report demonstrates reduced depression scores in a patient with postpartum depression, suggesting the efficacy of Bupleurum and Ying Wei method.
Objective: Based on the theory of "liver depression and Ying Wei imbalance", to explore the clinical efficacy and syndrome differentiation of Bupleurum combined with harmonizing Ying Wei method in the treatment of postpartum depression (PPD). Methods: the diagnosis and treatment process of a 28 year old patient with liver stagnation and blood deficiency type of PPD was reported. The Hamilton Depression Scale (HAMD) score and TCM four diagnosis syndrome were used as evaluation indexes to record the prescription adjustment strategy and curative effect outcome of the first, second and third diagnosis. Results: the initial HAMD score of the patient was 20, accompanied by depression, irritability, chest distress, palpitation, anorexia, insomnia, constipation and other diseases. After three stages of syndrome differentiation and treatment, the HAMD score was reduced to 10 points, and the physical symptoms were significantly improved: self perspiration stopped, constipation cleared, sleep became safe, and there was no recurrence during follow-up. Conclusion: Bupleurum (soothing liver depression and resolving depression) combined with harmonizing Ying Wei method (Guizhi formula) can significantly improve the emotional disorder and physical symptoms of patients with PPD, which reflects the clinical value of the pathogenesis theory of "liver depression and Ying Wei imbalance" in traditional Chinese medicine.
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Lü et al. (2025) studied this question.
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