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September 5, 2025Mediterranean Journal of Hematology and Infectious DiseasesOpen Access

Health-related quality of life measurement in adults with sickle cell disease in steady state: Experience of one French reference center

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Authors

GCGiovanna CannasHospices Civils de Lyon SPSolène PoutrelUniversité Claude Bernard Lyon 1 EVEmilie VirotUniversité Claude Bernard Lyon 1

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Implication

Analysis reveals significant impact of complications on quality of life in adults with sickle cell disease, suggesting improved hydroxyurea compliance may enhance outcomes.

Key Points

Substantial impairment in health-related quality of life was observed in adults with sickle cell disease due to frequent complications.
The study found a strong correlation between the sickle cell self-efficacy scale and the SF-36 scoring system for assessing quality of life.
Univariate and multivariate analyses indicated that recent hospitalization for sickle cell complications significantly impacts quality of life.
Higher compliance to hydroxyurea therapy was linked to improved scores in emotional role functioning, highlighting the importance of treatment adherence.

Cite This Study

Cannas et al. (2025) studied this question.

synapsesocial.com/papers/68bb46b56d6d5674bccfe850 https://doi.org/10.4084/mjhid.2025.065

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Implication

Analysis reveals significant impact of complications on quality of life in adults with sickle cell disease, suggesting improved hydroxyurea compliance may enhance outcomes.

Health-related quality of life measurement in adults with sickle cell disease in steady state: Experience of one French reference center

Discussion

Member takes

Implication

Key Points

Cite This Study

Health-related quality of life measurement in adults with sickle cell disease in steady state: Experience of one French reference center

Discussion

Member takes

Implication

Key Points

Cite This Study

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