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Integrating multi-omics approaches in acute myeloid leukemia (AML): Advancements and clinical implications

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Review demonstrates advancements in multi-omics integration for acute myeloid leukemia, highlighting personalized therapy and biomarker discovery.

Multi-omics approaches significantly enhance understanding of acute myeloid leukemia (AML) and treatment resistance.
Integration of genomics, proteomics, and metabolomics has unveiled novel biomarkers and therapeutic targets in AML.
Research leveraging high-throughput techniques has facilitated improved risk stratification and patient therapy selection.
Challenges remain in data integration complexity and ethical concerns, impacting the full realization of multi-omics in clinical practice.

Hamed Soleimani Samarkhazan (2025) studied this question.

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Review demonstrates advancements in multi-omics integration for acute myeloid leukemia, highlighting personalized therapy and biomarker discovery.