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September 5, 2025Sumatera Medical JournalOpen Access

Unveiling the Link Between Low Testosterone and Worsening Heart Failure Symptoms: A Literature Review

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Authors

RARaden Cecep Erwan ArdiansyahASAkhmad Sandy Sauqy

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Overview

Literature review reveals low testosterone worsens heart failure symptoms, indicating potential prognostic implications.

Key Points

  • Lower testosterone levels correlate with more severe heart failure symptoms and reduced quality of life.
  • Testosterone deficiency significantly affects myocardial contractility and energy metabolism in heart failure patients.
  • Men with heart failure and low testosterone experience higher mortality rates and worse prognosis.
  • A literature review highlighted the clinical impact of testosterone levels on heart failure outcomes across multiple studies.

Cite This Study

Ardiansyah et al. (2025) studied this question.

synapsesocial.com/papers/68bb46c96d6d5674bccff095https://doi.org/10.32734/sumej.v8i3.19752
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Low Testosteron Level in Worsening Symptom of Heart Failure Patients: A Literature Review2025
  2. 2Relation of Testosterone Levels to Mortality in Men With Heart Failure2018 · 28 citations
  3. 3Testosterone, cardiomyopathies, and heart failure2021 · 47 citations
  4. 4Metabolic Disturbances in Chronic Heart Failure: A Case for the “Macho” Approach with Testosterone?!2006 · 16 citations
  5. 5Testosterone: a natural tonic for the failing heart?2000 · 41 citations