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September 5, 2025Medical Science of Ukraine (MSU)Open Access

Analysis of Ph Level and Content of Main Inorganic Components in Oral Fluid and Its Excretion Rate in Adolescents With Juvenile Idiopathic Arthritis

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Authors

DKDenis A. KomarovНСН.М. Савєльєва

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Overview

Observational analysis reveals pH and inorganic component levels in oral fluid among adolescents with JIA, suggesting implications for caries risk management.

Key Points

  • Children with juvenile idiopathic arthritis had a pH of 7.50, higher than healthy controls at 7.00, indicating possible oral fluid changes.
  • Average oral fluid excretion rate was found to be 22% lower in JIA patients compared to the control group, suggesting a significant difference in salivary output.
  • Methotrexate treatment at doses above 15 mg correlated with 1.5-fold increased oral fluid excretion rate in JIA patients, indicating a potential dose-dependent response.
  • No significant differences were detected in calcium and phosphorus concentrations between JIA patients and controls, highlighting the complexity of oral biology.

Cite This Study

Komarov et al. (2025) studied this question.

synapsesocial.com/papers/68bb49bc6d6d5674bccff682https://doi.org/10.32345/2664-4738.2.2025.08
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Also Consider

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  1. 1AB1718 ULTRASONOGRAPHIC EVALUATION OF MAJOR SALIVARY GLANDS IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS: A COMPARATIVE CASE SERIES2024
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  3. 3Evaluation of Vitamin D level in patients with juvenile idiopathic arthritis and its relation to disease activity and disease subtypes2025
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