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September 5, 2025Medical Science of Ukraine (MSU)Open Access

Features of the Effect of Pneumoperitoneum on the Costal Part of the Diaphragm in the Presence of Mechanical Jaundice

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Authors

MKMyroslav KritsakІДІ. Я. ДЗЮБАНОВСЬКИЙТГТ. І. Гаргула

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Overview

Experimental analysis reveals that pneumoperitoneum exacerbates diaphragm changes during mechanical jaundice, indicating critical interactions.

Key Points

  • Mechanical jaundice led to significant muscle tissue restructuring in the diaphragm, marked by edema and degenerative changes.
  • Histological findings showed that after 3 hours of pneumoperitoneum, there were pronounced destructive changes in diaphragm tissues.
  • Bilirubin intoxication severely impacts microcirculation, enhancing the effects of pneumoperitoneum on diaphragm histology.
  • The study utilized 75 rats to explore the combined effects of mechanical jaundice and carbon dioxide insufflation on diaphragm structure.

Cite This Study

Kritsak et al. (2025) studied this question.

synapsesocial.com/papers/68bb49bc6d6d5674bccff685https://doi.org/10.32345/2664-4738.2.2025.07
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