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The roles of advanced glycation end products in cardiovascular diseases: from mechanisms to therapeutic strategies

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Advanced glycation end products significantly contribute to cardiovascular diseases by inducing oxidative stress and inflammation.
Both endogenous and exogenous advanced glycation end products affect cardiovascular tissues, leading to dysfunction and complications.
The pathways mediated by the AGE-RAGE axis are crucial in understanding the impact of advanced glycation end products on heart health.
Strategies to mitigate the effects of advanced glycation end products in cardiovascular diseases offer potential for new therapeutic approaches.

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This review examines advanced glycation end products' roles and mechanisms in cardiovascular diseases, highlighting emerging therapeutic strategies.

Li et al. (2025) studied this question.

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This review examines advanced glycation end products' roles and mechanisms in cardiovascular diseases, highlighting emerging therapeutic strategies.