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September 5, 2025Acta Anaesthesiologica BelgicaOpen Access

A comparative study to evaluate the effect of two different doses of tranexamic acid in reducing intraoperative blood loss during pancreaticobiliary surgeries

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Authors

DRDeepak RajPKPrakash KurumboorBSBhandari Shreya

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Overview

Randomized controlled trial compares tranexamic acid doses in reducing intraoperative blood loss during pancreaticobiliary surgeries, suggesting limited effect.

Key Points

  • No significant difference in intraoperative blood loss was found between the two tranexamic acid dosing groups.
  • Average blood loss was 553.0 ml in the bolus group compared to 423.0 ml in the combined regimen, with p=0.17.
  • Both dosing strategies showed similar change in hematocrit and lengths of hospital stay, indicating equivalence.
  • No thrombotic complications were reported in either group, pointing to the safety of both tranexamic acid regimens.

Cite This Study

Raj et al. (2025) studied this question.

synapsesocial.com/papers/68bb49cc6d6d5674bccffd21https://doi.org/10.56126/76.3.25
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