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September 5, 2025Open Access

Risk factors for clinically relevant postoperative pancreatic fistula after pancreatectomy: a retrospective observational study

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Authors

SZShenghao ZhangHLHao LiGCGuoliang Cao

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Overview

Retrospective observational study finds key risk factors for postoperative pancreatic fistula, suggesting better patient management strategies.

Key Points

  • Twenty percent of patients developed clinically relevant postoperative pancreatic fistula after pancreatectomy.
  • Independent risk factors included a positive drainage fluid culture, elevated white blood cell count, and high C-reactive protein levels.
  • Multivariate analysis determined specific thresholds for serum calcium, white blood cell count, and operation time as significant risk factors.
  • Postoperative monitoring for intra-abdominal infections and inflammatory markers is vital to reducing the risk of complications.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68bb49db6d6d5674bcd0035dhttps://doi.org/10.21203/rs.3.rs-7047314/v1
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